In the medical press there has been much debate about the lack of clinical pharmacology and therapeutics teaching in medical schools—with a suggestion that. Oxford textbook of clinical pharmacology and drug therapy Related Articles. Clinical Pharmacology of Psychotherapeutic Drugs (3rd edn). Trends in. D. G. Grahame-Smith and J. K. Aronson. Oxford University Press, Oxford, UK, ISBN Hbk £, pbk £ pp.
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PDF | On Jan 1, , Daniel M Sado and others published Oxford Textbook of Clinical Pharmacology and Drug Therapy. PDF | On Jun 1, , Ross J Taylor and others published OXFORD TEXTBOOK OF CLINICAL PHARMACOLOGY AND DRUG THERAPY: second edition. OXFORD TEXTBOOK OF CLINICAL PHARMACOLOGY AND DRUG THERAPY Get a printable copy (PDF file) of the complete article (K), or click on a.
The preface of the first edition of this book, published in , starts: The preface of the third edition acknowledges that much has changed, even since the second edition, particularly in relation to the rise of evidence-based medicine and the development of detailed guidelines on the management of common clinical problems. The book is set out in four sections. Section 1 pp. Section 2 23 pp. Section 3 pp. Section 4 pp.
My only criticism of this whole section is that it lacks an account of the role of the clinical pharmacologist in both laboratory and hospital medicine. What sort of patients should be referred to a clinical pharmacologist?
The third section adopts a systems-based format to discuss the pharmacological treatments of common medical and surgical conditions. Although these recommendations are well explained and easy to read, I would have welcomed more information on the quality of the evidence. For example, a treatment with an excellent evidence base could have been given two stars, a treatment with moderate evidence one star and a treatment with no evidence no star.
These parts of the text might usefully have been referenced. I was disappointed by the chapter on immunological therapies.
It provides a basic explanation of the four types of hypersensitivity reaction but no account of the inflammatory mediators involved—essential information for an understanding of immunomodulatory anti-inflammatory agents and the cytokine-antibody therapies now being used in rheumatoid arthritis and Crohn's disease. The last section is a pharmacopoeia—in effect, short notes on all the commonly prescribed drugs.
This will be useful for fast information and last-minute revision before exams. ISBN The preface of the third edition acknowledges that much has changed, even since the second edition, particularly in relation to the rise of evidence-based medicine and the development of detailed guidelines on the management of common clinical problems. The book is set out in four sections.
Section 1 pp. Section 2 23 pp.
Section 3 pp. Section 4 pp.
Would I recommend this book to students? Section 1 provides a very clear account of the scientific basis of drug therapy.
Sometimes dry principles such as pharmacokinetics and pharmacodynamics are enlivened by excellent clinical examples. I would certainly recommend this section to students as a source of information about these aspects of drug therapy. However, Section 1 also contains some very cursory references to complex issues such as patient compliance, drug costs, drug formularies and national bodies such as NICE, who are charged with providing guidance about evidence-based prescribing.
What little there is of Section 2 is excellent, but only as far as it goes.
It provides a clear account of the questions that a prescriber should ask before prescribing a drug. This includes the crucial question: should a drug be prescribed at all?
However, it does not address the question of which drugs are available and why. Nor could I find any reference to guidelines, either local or national, as a source of information to answer the questions that are posed, or to audit as a means of critically evaluating individual prescribers or the organizations in which they work.
This applies the principles of prescribing described in Section 2 in a clear, concise manner, while adding additional, relevant information about antimicrobial chemotherapy and resistance to antimicrobials. The authors do not shy away from providing recommendations for the treatment of specific infections, and these are very much in line with our local antibiotic policy and with national recommendations, such as the PHLS guidance on treatment of infections in the community.
I would have no hesitation in recommending this section to students as a basic source of information about antimicrobial chemotherapy.