Discover the best Veterinary Virology in Best Sellers. Find the top most popular items in site Books Best Sellers. Fenner's Veterinary Virology, Fifth Edition, is a comprehensive reference of global importance that features coverage on viral. Fenner's Veterinary, Virology, Fourth Edition, is the long awaited New author team - one main author to ensure that the book.
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Veterinary Virology deals with basic biomedical virology and the clinical discipline of infectious diseases. The book discusses the principles of virology as . download Fenner's Veterinary Virology - 5th Edition. Print Book & E-Book. ISBN , download Veterinary Virology - 3rd Edition. Print Book & E-Book. ISBN ,
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About Frederick A.
Frederick A. Librarian Note: There is more than one author in the Goodreads database with this name. Books by Frederick A. The matrix protein gives rigidity to the viron morphology, e. In certain other viruses like arena viruses, bunyaviruses and corona viruses there is no matrix protein and are therefore more pleomorphic.
The envelope is also possessed by certain icosahedral viruses like African swine fever virus, herpes viruses, toga viruses, flaviviruses and retroviruses. The envelope is immunogenic and is required for infectivity but in some poxviruses which have an envelope the infectivity is not dependent on the envelope.
Complex symmetry: Some viruses like poxviruses have a dumbell shaped core surrounded by complex membranes and other icosahedral or helical symmetry. The retroviruses have a tubular nucleocapsid surrounded by an icosahedral capsid enclosed within an envelope. The essential components of infectious virus particles are nucleic acid and protein.
The enveloped viruses contain lipids and carbohydrates in their glycoprotein peplomeres. The complex viruses like pox viruses also contain lipids. The chemical composition of viruses can only be determined when the viruses are obtained in a pure form as the viruses contain host cell constituents.
Most of the virus particles are attached to cell debris having almost similar chemical properties. Therefore, until , without the introduction of more refined methods of purification, the animal viruses were not purified sufficiently for their chemical analysis.
The other reasons of delay in purification of animal viruses was the small quantity of virus material available. With the introduction of tissue culture, it is now possible to obtain sutlicient vIrUS for chemical analysis.
In the purificaiton of viruses differential ultracentrifugation leads Structure and Composition to their considerable purification. The important technique introduced in 's is density gradient centrifugation where sucrose gradients ensure finer separation of particles with different sedimentation properties.
Density gradients of these salts are prepared and the mixture of virus and host cell debris is centrifuged in a high speed centrifuge. The different particles take positions in the gradient according to their buoyant density. The viruses can also be separated from contaminating material by using fluorocarbons or other organic solvents; mild detergents to remove host cell material selectively - especially for removing lipid material and denatured host protein.
The enveloped viruses cannot be purified by detergents or lipid solvents because they are disrupted due to the action of these agents.
The non enveloped viruses or naked viruses are stable in lipid solvents or even in strong detergents like sodium dodecyl sulphate.
Nucleic acid: Any particular virus contains either DNA or RNA which may be either single stranded or double stranded and the genome consists of either one molecule or several molecules.
In most of DNA viruses the genome consists of a single molecule while several RNA viruses contain the genome of several molecules. The genome may be of linear or circular configuration.