Presentamos un paciente afectado por un síndrome serotoninérgico inducido por fluoxetina y selegilina que se manifestó con encefalopatía, mioclonías. Download PDF. More article options. ePub Síndrome serotoninérgico por interacción entre linezolid y 5-hidroxitriptófano. Serotoninergic syndrome due to. otras medicinas (o ambos) si se sospecha la presencia del síndrome serotoninérgico. Los casos de síndrome serotoninérgico denunciados en.
|Language:||English, Spanish, German|
|Genre:||Academic & Education|
|ePub File Size:||26.72 MB|
|PDF File Size:||11.51 MB|
|Distribution:||Free* [*Sign up for free]|
Request PDF on ResearchGate | On Feb 1, , Eva Hernández-Lorente and others published Síndrome serotoninérgico desencadenado por linezolid. PALAVRAS-CHAVE: síndrome serotoninérgica, paroxetina, mioclonia. É causada por adição ou aumento na dose de agente serotoninérgico, apresentando. Am J Psychiatry , Revisión de 38 casos: 10 comunicaciones de casos y 2 series→Criterios diagnósticos del Síndrome serotoninérgico.
Corresponding author. Introduction Garcinia cambogia, also known as the Malabar tamarind, is a plant that is commonly used in India and Southeast Asia for its sour taste and as a food-bulking agent [ 1 ]. The plant contains hydroxycitric acid HCA and has recently become a popular ingredient in over-the-counter supplements designed for weight loss and weight management [ 2 ]. There is limited evidence that HCA may increase serotonin concentrations and thereby increase the risk of serotonin toxicity. HCA analogs increase serotonin concentrations within the brains of rats [ 1 , 3 ], and randomized human studies have found elevations in free serum serotonin concentrations after the administration of HCA derivatives [ 4 ]. We report a case of suspected serotonin toxicity in the presence of therapeutic dosing of serotonin reuptake inhibitors SSRIs when combined with a nutritional supplement containing G. Case Presentation A year-old woman was in her normal state of health when she developed stuttering speech and profuse sweating.
This suggests that dentists believe pulpotomy is a more definitive and successful treatment for reversible pulpitis and are unwilling to attempt the more conservative IPT.
One factor that was not directly addressed in this questionnaire, but which could explain why dentists would prefer pulpotomy over IPT, is the difficulty in accurately diagnosing pulpal status.
IPT is only indicated in a tooth with a healthy or reversibly inflamed pulp. Since there is no reliable method to determine pulpal status other than a clinical determination based on the reported history of symptoms many dentists are reluctant to initiate IPT.
There are clear differences in the attitudes of pdiatrie and general dentists regarding IPT treatment planning. This study illustrates that general dentists are more willing to attempt IPT on primary teeth than pdiatrie dentists. In every case scenario presented where IPT was an appropriate choice, general dentists were more likely to select it as their preferred treatment.
Pdiatrie dentists as a group indieate they are most eomfortable with the more traditionally aeeepted pulpotomy as their ehoiee for vital pulp therapy.
This may be explained by the historie importanee of the pulpotomy in pdiatrie dentistry and pdiatrie dentists' resistance to incorporating new treatment options into their practice.
It may also be explained by the fact pdiatrie dentists have more training in performing pulpotomies. There are significant differences in the materials utilized by pdiatrie and general dentists for both pulpotomy and IPT. Both groups indieated formoeresol is still the most popular ehoiee for a pulpotomy medieament, despite published eoneerns regarding its potential toxicity. General dentists as a group preferred full-strength formocresol while the majority of pdiatrie dentists prefer diluted formocresol.
Full-strength and diluted formocresol have been shown to have similar success rates, thus suggesting the difference is elinieally insignificant. While both preferred a 1-step technique, most pdiatrie dentists indicated they would place glass ionomer after caries removal while general dentists as a group preferred placing calcium hydroxide. Both materials have been evaluated and have similar success rates, again suggesting a clinically insignificant differenee in preferenee. General dentists were mueh less likely to restore with a stainless steel crown than pdiatrie dentists.
In lieu of full coverage, most general dentists indicated composite resin would be their restoration of choice. IPT has been shown to be significantly more successful when combined with full-coverage stainless steel than when combined with an intracoronal restoration. A large pereentage of partieipants indieated they would attempt a pulpotomy on a tooth that was irreversibly inflamed based on the accompanying history of spontaneous nocturnal pain. This reinforces the importance of a clinician's diagnostic skills in selecting the appropriate form of pulp treatment.
This study's major limitations include the low overall response rate to the questionnaire and the signifieant differenee in sample sizes of the 2 study groups.
The sample size diserepaney can be attributed to the way in which participants of the 2 groups were recruited. Pdiatrie dentists were identified and contacted through information provided by the AAPD.
General dentists were seleeted from a list purehased from a eompany speeializing in medical and dental provider information for marketing purposes. Requests to participate were sent to approximately equal numbers of dentists from each group. Contact information obtained for general dentists proved to be less reliable, yielding fewer results and creating a discrepancy in sample sizes.
This sample size difference could potentially bias the results and allowed for less precise estimates for the smaller general dentist study group. The results reported in the study suggest there is no current consensus as to whieh form of vital pulp therapy is most appropriate for primary teeth.
Though the use of IPT has increased over the past decades, the study results suggest that it is still less utilized than pulpotomy. For IPT to become the standard of care for vital primary teeth with deep caries, dentists need better education in the diagnosis of pulpal status, indications for IPT, and its reported success compared to pulpotomy.
In a case of deep decay in a primary molar where indirect pulp therapy is an appropriate treatment option, the majority of respondents would treatment plan a pulpotomy and significantly more general dentists would perform IPT than pdiatrie dentists. Most surveyed believe that pulpotomy is more successful than IPT. There are significant differences between pdiatrie and general dentists in terms of treatment planning and materials utilized in vital pulp therapy.
There is no consensus among dentists as to which vital pulp therapy is most appropriate for primary teeth. Acknowledgement The authors wish to thank James A. Coll, clinical professor. Department of Pdiatrie Dentistry, University of Maryland Dental School, Baltimore, Md, for providing a portion of the clinical cases and radiographs used in this survey.
References 1. American Academy of Pdiatrie Dentistry. Guidelines on pulp therapy for primary and immature permanent teeth: Reference manual Pediatr Dent ; Coll JA.
Indirect pulp capping and primary teeth: Is the primary tooth pulpotomy out of date?
Pediatr Dent ; Bjorndal L. The caries process and its effect on the pulp: the science is changing and so is our understanding. Indirect pulp treatment of primary posterior teeth: A retrospective study. Indirect pulp treatment: In vivo outcomes of an adhesive resin system vs calcium hydroxide for protection of the dentin pulp complex.
Psychiatry Clin Neurosc ; Ebert D.
Albert R, May A, et al. The serotonin syndrome and psychosis-like side-effects of fluvoxamine clinical usean estimation of incidence. Eur Neuropsychopharmacology ; Bertorini TE. Myoglobinyria, malignant hyperthermia, neuroleptic malignant syndrome and serotonin syndrome. Neurol Clin ; Dike GL. Trifasic waves in serotonin syndrome.
J Neurol Neurosurg Psychiatry ; Morphological and functional studies on the serotoninergic inervation of the inferior olive. J Physiol Paris ; Behavioral effects of 5-hydroxy-N-acetyltryptophan, a putative synthetic precursor of N-acetylserotonin. Progr Neuropsychopharmacol Biol Psychiatry ; The effects of serotonergic stimulation on hippocampal and neocortical slow and behavior.
Brain Res; Drug-induced hyperthermia Anaesthesia ; Review of pharmachology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine MDMA or "ecstasy".
Psychopharmacology Berl ; Brubacher JR.
Serotonin syndrome from velaxine-tranylcylpromine interaction Vet Hum Toxicol ; Analysis of the 5-HT1A receptor involvement in passive avoidance in the rat. Br J Pharmacol ; Martin TG.
Serotonin syndrome Ann Emerg Med ; Mitchell PB. Drug interactions of clinical significance with selective serotonin reuptake inhibitors Drug Saf ; Ruiz F.
Fluoxetine and the serotonin syndrome. Ann Emerg Med ; McKay CA Jr. Serotonin syndrome:case report and review of the literature. Conn Med ; Lucki I, Frazer A. Prevention of the serotonin syndrome in rats by repeated administration of monoamine oxidase inhibitors but not tricyclic antidepressants.
Psychopharmacocology Berl ; The serotonin syndrome:case responsive to propanolol J Clin Psychopharmacol ; Treatment of the serotonin syndrome with cyproheptadine.
N Engl J Med